Sohrab Rohani (P. Eng, FCIC)
Professor of Chemical and Bio-Chemical
Department of Chemical & Biochemical Engineering
Faculty of Engineering ,
The University of Western Ontario
Dr. Rohani is the past Chair of Chemical and Biochemical Engineering Department at the University of Western Ontario. He obtained his B.Sc. in Chemical Engineering from Pahlavi (Shiraz) University and his Ph.D. from the University of Wales in Process Control. He spent two years at the Swiss Federal Institute of Technology (ETH) in Zurich before joining the Chemical Engineering Department of the University of Saskatchewan in 1982. He has spent sabbatical leaves at the University of Manchester, Institute of Science and Technology (UMIST), England; ETH (Switzerland); the Ecole Nationale Superieure des Industries Chimiques (ENSIC), Nancy, France; and ApotexPharmaChem Inc. (Canada). He has been the recipient of Engineering Medal in Research and Development from the Professional Engineers, Ontario, in 2008 and Western Faculty of Engineering Award for Excellence in Research in 2009.
Dr. Rohani has over 200 refereed publications. He is a registered professional engineer in Ontario and a Fellow of Chemical Institute of Canada (FCIC). His main areas of research are in the development and control of active pharmaceutical ingredients, process control applications, zeolitic nanomaterials and TiO2 nanophotocatalysts.
Dr. Rohani's research in the area of Crystallization includes detailed experimental study of the kinetics of nucleation, growth, agglomeration, and breakage in batch and continuous systems. Study of the effect of additives, control of crystal size distribution (CSD) and polymorphic distribution, and development of instrumentation for the control of pilot plants and industrial continuous cooling crystallizers. Recovery of protein from oilseeds such as canola and sunflower seeds by precipitation in a tubular reactor and detailed modeling of the particle size distribution are also investigated. The effect of micro-, meso- and macro-mixing on the size distribution, shape and morphology of the product in precipitation processes is being studied, both experimentally and theoretically.
In the area of Process Control, two processes are considered to study the efficacy of various control algorithms: batch and continuous crystallization processes and the fluid catalytic cracking (FCC) process. Uni- and multi-variable model predictive control algorithms using linear and non-linear models including artificial neural networks are being studied. The geometric non-linear control and the dynamic optimal control are also applied to a batch crystallizer.
Prof. Rohani's research in the field of nanomaterials includes fundamental and applied research on manufacturing techniques, characterization, properties and environmental applications of zeolitic like framework nano materials including nano zeolites, metal organic frameworks (MOFs), zeolitic imidazolate frameworks (ZIFs), mesoporous materials, TiO2 nanotubes and nanoparticles, and preparation of super-hydrophobic surfaces.
Ongoing Projects in CCPL and ZNML laboratories
The Control and Crystallization of Pharmaceuticals Laboratory in the University of Western Ontario ( CCPL-Western) provides expertise and state-of-the-art technology and instrumentation for the study of crystallization of bulk chemicals, fine chemicals and pharmaceuticals. In particular crystal engineering is used for the process and product design in the following major areas:
Control of continuous and batch crystallizers and development of a highly efficient numerical algorithm for the solution of the population balance equation
Develop on-line sensors for the measurement of crystal suspension density, supersaturation and crystal shape, and
Screening, characterization and control of polymorphism of pharmaceuticals and fine chemicals
Due to the importance of zeolitic-like frame work materials such as metal organic frameworks with huge industrial potential in various areas including oil industries, fine chemicals, pharmaceuticals, and environmental applications, we have recently established the Zeolitic and Nano Materials Laboratory (ZNML).
The objectives of the ZNML are:
- Develop novel rapid fabrication technologies for the synthesis of zeolite-like frameworks by means of solvo-thermal microwave and ultrasonic energies.
- Systematic study of CO2 capturing and hydrogen storage by zeolite-like framework materials.
- Application of novel zeolite-like frameworks for controlled in-vitro drug release.
- Synthesis of nano-sized Y-zeolites in mesoporous silica particles.
- New functional zeolite-like frameworks for enantio-selective separation of pharmaceuticals.
- Fabrication of zeolite-like frameworks thin layer membranes and investigation of their separation properties.
- Mixed matrix membranes based on zeolite-like frameworks materials/polymer membranes for gas separation.
- Environmental catalysts based metal cluster nano particles such as gold nano particles (GNP) loaded on zeolite-like frameworks for CO oxidation, NOx reduction etc.
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Thompson Eng. Bld., Rm. 457
Department of Chemical and Biochemical Engineering
Faculty of Engineering
Canada N6A 5B9
Fax: 1-519- 661-3498